Ion Chromatography IC is chromatography technique where ions or polar molecules are separated based on their affinity to the ion exchanger.

High-performance anion-exchange chromatography (HPAE) coupled with pulsed amperometric detection (PAD) is a well-established technique to identify and

quantify carbohydrates. With HPAE, carbohydrates are ionized in the strong base eluent (NaOH/NaAc) and separated by anion-exchange chromatography. Gradient elution can be used to get better resolution by changing Ion strength of the eluent.

Thermo ISQ EC-IC is single quadrupole mass spectrometer which can be coupled to Agilent 1100 HPLC or Dionex ICS5000 chromatography systems. Direct injection is possible via syringe pump.

Dionex 5000 ICS plus is High Performance Anion Exchange Chromatography HPAE system for quantitative carbohydrate analysis. System consist a high pressure quaternary gradient pump, thermostated autosampler, column compartment, Pulse Amperometric Detector PAD with gold electrode which is sensitive and selective detector for carbohydrates.

System has a supressor to convert NaOH/NaAc eluent to water and conductivity detector for MS connection or other IC applications.

Thermo ISQ EC-IC is unit resolution single quadrupole MS with mass range 10-1250 m/z. ESI source can be operated +/- polarity or fast polarity switching.